S.E.M.I.: Side Effects May Include...

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S.E.M.I.: Side Effects May Include...

Main Game

S.E.M.I. is a cooperative online game about escaping from a special clinic. Here you and up to 3 of your feeble-minded loyal friends in the role of patients fight with the staff and other patients and find yourself in unexpected situations. Teamwork is essential, as randomized events and experimental drugs will lead your party into unpredictable mayhem. Pop pills with your friends as you cooperate to gain your freedom.

ActionComedyPartyArcadeHack and slash/Beat 'em upIndie
Game modes
Co-operativeMultiplayerSingle player
Player perspectives
Third person

Prices

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Release dates

PC (Microsoft Windows)November 20, 2025
Released ✓
PC (Microsoft Windows)January 23, 2026
Released ✓